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Zhuzhou Yuancheng Hezhong Technology Development Co., Ltd.
Zhuzhou Yuancheng Hezhong Technology Development Co., Ltd.
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CAS 51-05-8 Healthy Raw Materials / Procaine HCl Powder Anesthetic Anodyne

CAS 51-05-8 Healthy Raw Materials / Procaine HCl Powder Anesthetic Anodyne

Brand Name : purity
Model Number : 51-05-8
Certification : gmp iso9001
Place of Origin : chiha
MOQ : 1g
Payment Terms : T/T, Western Union, MoneyGram
Supply Ability : 1000kg/month
Packaging Details : foil bags or stealth
EINECS : 200-077-2
Molecular formula : C30H44O3
Molecular weight : 452.67
CAS register number : 51-05-8
Assay : 99%
Product name : aminocaine, anadolor, anesthesol
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White Powder Local Anesthetic Anodyne Procaine Hydrochloride Anadolor 51-05-8

Procaine
Alias: aminocaine;anadolor;anesthesol;anestil;atoxicocaine;Benzoicacid
CAS: 51-05-8
EINECS: 200-077-2
M.F.: C13H21ClN2O2
M.W.: 272.77
M.P.: 155-156 °C
Product Description: white crystalline powder
Usage: local anesthetic used as a pharmaceutical intermediate for infiltration anesthesia, nerve block.
Description:
Procaine HCl is a local anesthetic drug of the amino ester group. It is used primarily to reduce the pain of intramuscular injection of penicillin, and it is also used in dentistry. Owing to the ubiquity of the trade name Novocain, in some regions procaine is referred to generically as novocaine. It acts mainly by being a sodium channel blocker.Today it is used therapeutically in some countries due to its sympatholytic, anti-inflammatory, perfusion enhancing, and mood enhancing effects.
Procaine HCl is indicated for the production of local or regional analgesia and anesthesia by local infiltration and peripheral nerve block techniques.
Applications:
Application of procaine leads to the depression of neuronal activity. The depression causes the nervous system to become hypersensitive producing restlessness and shaking, leading to minor to severe convulsions. Studies on animals have shown the use of procaine led to the increase of dopamine and serotonin levels in the brain.Other issues may occur because of varying individual tolerance to procaine dosage. Nervousness and dizziness can arise from the excitation of the central nervous system, which may lead to respiratory failure if overdosed. Procaine may also induce weakening of the myocardium leading to cardiac arrest.
Procaine can also cause allergic reactions causing the individuals to have problems with breathing, rashes, and swelling. Allergic reactions to procaine are usually not in response to procaine itself, but to its metabolite PABA. About one in 3000 people have an atypical form of pseudocholinesterase,[citation needed] which does not hydrolyze ester anesthetics such as procaine, resulting in a prolonged period of high levels of the anesthetic in the blood and increased toxicity.

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Product NameProcaine Hydrochloride
Other Name4-Aminobenzoic acid 2-(diethylamino)ethyl ester hydrochloride
Assay (%)≥99.00OdorCharacteristic
ColorWhite crystalline powderCas No.51-05-8
Molecular FormulaC13H20N2O2.HClMolecular Weight272.77
StandardUSP34/BP2005

Function
Main functions are as follows:
1.Local anesthetic.
ApplicationsMain applications are as follows:
Applied in pharmaceuticalfields.
Packing1kgor 5kg/bag, 25kg/drum
Shelf Life24 months
StorageStore in sealed containers at cool & dry place. Protect from light, moisture and pest infestation.
Test ItemsSpecificationTest Results
AppearanceWhite crystals or a white crystalline powderConform
IdentificationABE. It appears positive reaction
Melting point154degree~158degree154degree~157degree
AcidityPH 5.0~6.5PH=5.9
Appearance of solutionClear and colourlessConform
Loss on drying≤0.5%0.07%
Heavy metals≤0.0005%Conform
Related substances≤0.05%Conform
Sulphated ash≤0.1%0.05%
Assay ( on dry basis )99.0-101.0%99.87%
ConclusionConform to BP2005

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