Huperzine A Introduction
Huperzine A is one of the alkaloids contained in a plant known as
Chinese club moss. It can be grown in Hawaii, but not in any other
part of this country. Huperzine A and huperzine B are two of the
chemicals that have been separated from Chinese club moss.
Huperzine B is also an acetylcholinesterase inhibitor, but because
its effects are much weaker than those of huperzine A.
Huperzine A has also been combined or "hybridized" with the
prescription drug tacrine (Cognex), an acetylcholinesterase
inhibitor approved by the U.S. Food and Drug Administration (FDA)
for treating Alzheimer's disease. The resulting "huprine"
combination seems to be more effective at limiting
acetylcholinesterase activity than either agent alone. Much more
study needs to be done on the possible effects of huperzine A,
huperzine B, huprine, and other chemicals derived from Chinese club
Huperzine A Application
1) Improve the efficiency of learning and memory
2) Treat myasthenia
3) Used in senile amnesia and senile dementia